BDBM436621 (S)-2-methoxy-9- methyl-6-(2-methyl- 4-(3-(methylamino)- 1-(thiophen-2- yl)propoxy)benzyl)- 6,7,8,9-tetrahydro- 5H-pyrimido[4,5- e][1,4]diazepin-5-one::US10590140, Example 397

SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)c(C)c1)c1cccs1

InChI Key InChIKey=GVFOVIPQFRUEHA-NRFANRHFSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436621   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103](Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM436621((S)-2-methoxy-9- methyl-6-(2-methyl- 4-(3-(methyla...)
Affinity DataKi: <100nMAssay Description:α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent