BDBM436995 6-(4-Fluoro-3-methyl-phenyl)-1-(2-oxobutyl)-3H-imidazo[4,5-b]pyridin-2- one::US10617676, Example 331::US11207298, Example 331

SMILES CCC(=O)Cn1c2cc(cnc2[nH]c1=O)-c1ccc(F)c(C)c1

InChI Key InChIKey=DEHZJGNEFCRBIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436995   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436995(6-(4-Fluoro-3-methyl-phenyl)-1-(2-oxobutyl)-3H-imi...)
Affinity DataIC50:  12nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436995(6-(4-Fluoro-3-methyl-phenyl)-1-(2-oxobutyl)-3H-imi...)
Affinity DataIC50:  12nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent