BDBM437046 6-[4-Fluoro-3-(trifluoromethyl)phenyl]-3-methyl-1-(pyridazin-3- ylmethyl)imidazo[4,5-b]pyridin-2-one::US10617676, Example 382::US11207298, Example 382

SMILES Cn1c2ncc(cc2n(Cc2cccnn2)c1=O)-c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=SFVMMVWLGJROOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437046   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437046(6-[4-Fluoro-3-(trifluoromethyl)phenyl]-3-methyl-1-...)
Affinity DataIC50:  16nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437046(6-[4-Fluoro-3-(trifluoromethyl)phenyl]-3-methyl-1-...)
Affinity DataIC50:  16nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent