BDBM437111 2-[6-(3-Chloro-4-fluoro-phenyl)-2-oxo-3H-imidazo[4,5-b]pyridin-1-yl]-N- cyclopropyl-acetamide::US10617676, Example 448::US11207298, Example 448

SMILES Fc1ccc(cc1Cl)-c1cnc2[nH]c(=O)n(CC(=O)NC3CC3)c2c1

InChI Key InChIKey=GQHKPBAPXWZJIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437111   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437111(2-[6-(3-Chloro-4-fluoro-phenyl)-2-oxo-3H-imidazo[4...)
Affinity DataIC50:  8nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437111(2-[6-(3-Chloro-4-fluoro-phenyl)-2-oxo-3H-imidazo[4...)
Affinity DataIC50:  8nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent