BDBM437601 2-chloro-6-(4-(1-methyl-4-(2-morpholinopyrimidin-5-yl)- 6-oxo-1,6-dihydropyridin-3-yl)-1H-pyrazol-1- yl)benzonitrile::US10617680, Example 335::US11020380, Example 335

SMILES Cn1cc(-c2cnn(c2)-c2cccc(Cl)c2C#N)c(cc1=O)-c1cnc(nc1)N1CCOCC1

InChI Key InChIKey=WQAOKTLAMXTRBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437601   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437601(2-chloro-6-(4-(1-methyl-4-(2-morpholinopyrimidin-5...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437601(2-chloro-6-(4-(1-methyl-4-(2-morpholinopyrimidin-5...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent