BDBM437842 (2S)-N-[[2-cyclopropyl-6-[2- (trifluoromethyl)pyrimidin-5- yl]pyrimidin-4-yl]methyl]-3- (4-fluorophenyl)sulfonyl-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 10

SMILES Fc1ccc(cc1)S(=O)(=O)N1C2CC(C2)[C@H]1C(=O)NCc1cc(nc(n1)C1CC1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=NUYHSFBWLFRWTA-LREWSXEPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437842   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM437842((2S)-N-[[2-cyclopropyl-6-[2- (trifluoromethyl)pyri...)
Affinity DataIC50:  2.15nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent