BDBM437842 (2S)-N-[[2-cyclopropyl-6-[2- (trifluoromethyl)pyrimidin-5- yl]pyrimidin-4-yl]methyl]-3- (4-fluorophenyl)sulfonyl-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 10
SMILES Fc1ccc(cc1)S(=O)(=O)N1C2CC(C2)[C@H]1C(=O)NCc1cc(nc(n1)C1CC1)-c1cnc(nc1)C(F)(F)F
InChI Key InChIKey=NUYHSFBWLFRWTA-LREWSXEPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 437842
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 2.15nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair