BDBM437896 (2S)-N-[[5-(difluoromethyl)-2- [2-(trifluoromethyl)pyrimidin- 5-yl]-4-pyridyl]methyl]-3-(4- fluorophenyl)sulfonyl-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 24

SMILES FC(F)c1cnc(cc1CNC(=O)[C@@H]1C2CC(C2)N1S(=O)(=O)c1ccc(F)cc1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=JPKCFBGTYVDSPZ-AEABFECFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437896   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM437896((2S)-N-[[5-(difluoromethyl)-2- [2-(trifluoromethyl...)
Affinity DataIC50:  9.92nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent