BDBM437920 (2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- (trifluoromethyl)-1-[2- (trifluoromethyl)pyrimidin-5- yl]pyrazol-4-yl]methyl]-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 29

SMILES Fc1ccc(cc1)S(=O)(=O)N1C2CC(C2)[C@H]1C(=O)NCc1cn(nc1C(F)(F)F)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=NAPQARDRNYNOME-AVVITEIWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437920   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM437920((2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- (trifluoro...)
Affinity DataIC50:  4.84nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent