BDBM437920 (2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- (trifluoromethyl)-1-[2- (trifluoromethyl)pyrimidin-5- yl]pyrazol-4-yl]methyl]-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 29
SMILES Fc1ccc(cc1)S(=O)(=O)N1C2CC(C2)[C@H]1C(=O)NCc1cn(nc1C(F)(F)F)-c1cnc(nc1)C(F)(F)F
InChI Key InChIKey=NAPQARDRNYNOME-AVVITEIWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 437920
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 4.84nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair