BDBM438128 US10597367, Example 121

SMILES Cc1cc(nc(n1)-c1cccc(c1)-c1cc(F)cc(c1)C(O)=O)-c1ccoc1

InChI Key InChIKey=WOBDJQJQBFCJNI-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 438128   

TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM438128(US10597367, Example 121)
Affinity DataEC50:  350nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM438128(US10597367, Example 121)
Affinity DataEC50:  1.56E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM438128(US10597367, Example 121)
Affinity DataEC50:  2.21E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM438128(US10597367, Example 121)
Affinity DataEC50:  310nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent