BDBM438345 US10618897, Example 166::US10618897, Example 167

SMILES FC(F)(F)CNC(=O)CN1C(=O)C2(CCN(C2)C(=O)c2ccc3[nH]ncc3c2)c2c1cccc2Cl

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438345   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM438345(US10618897, Example 166 | US10618897, Example 167)
Affinity DataIC50:  4.76E+4nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM438345(US10618897, Example 166 | US10618897, Example 167)
Affinity DataIC50:  799nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent