BDBM438353 N-(4-fluorophenyl)-2-methyl-5-(pyridin-2- ethynyl)benzamide::US10618900, No. ZD040

SMILES Cc1ccc(cc1C(=O)Nc1ccc(F)cc1)C#Cc1ccccn1

InChI Key InChIKey=GFVIHPBIWVOOKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438353   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM438353(N-(4-fluorophenyl)-2-methyl-5-(pyridin-2- ethynyl)...)
Affinity DataIC50:  1.04E+5nMAssay Description:Experimental material: HEK293/mGluR5 cell line, Fluo-8 calcium ion fluorescent dye, positive control MPEP, CTEPExperimental instrument: FLIPR Tetra r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent