BDBM438368 3-((2-methylthiazol-4-ylethynyl)-N- phenylbenzamide::US10618900, No. ZD014

SMILES Cc1nc(cs1)C#Cc1cccc(c1)C(=O)Nc1ccccc1

InChI Key InChIKey=ZLXWQZYFVQDJQB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438368   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM438368(3-((2-methylthiazol-4-ylethynyl)-N- phenylbenzamid...)
Affinity DataIC50:  1.48E+4nMAssay Description:Experimental material: HEK293/mGluR5 cell line, Fluo-8 calcium ion fluorescent dye, positive control MPEP, CTEPExperimental instrument: FLIPR Tetra r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM438368(3-((2-methylthiazol-4-ylethynyl)-N- phenylbenzamid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Experimental material: HEK293/mGluR5 cell line, Fluo-8 calcium ion fluorescent dye, positive control MPEP, CTEPExperimental instrument: FLIPR Tetra r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM438368(3-((2-methylthiazol-4-ylethynyl)-N- phenylbenzamid...)
Affinity DataIC50:  1.48E+4nMAssay Description:Experimental material: HEK293/mGluR5 cell line, Fluo-8 calcium ion fluorescent dye, positive control MPEP, CTEPExperimental instrument: FLIPR Tetra r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent