BDBM439322 (S)-5-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)-4-methoxybutanamido)-1H-indole-2-carboxylic acid::US10633375, Compound No. 2::US11084808, Compound 2

SMILES COCC[C@@H](C(=O)Nc1ccc2[nH]c(cc2c1)C(O)=O)n1cc(OC)c(cc1=O)-c1cc(Cl)ccc1C(C)=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439322   

TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439322((S)-5-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50:  19nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439322((S)-5-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50:  19nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent