BDBM439339 4-(2-(4-(2-butyryl-5-chlorophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)-3-phenylpropanamido)benzoic acid::US10633375, Compound No. 21::US11084808, Compound 21

SMILES CCCC(=O)c1ccc(Cl)cc1-c1cc(=O)n(cc1OC)C(Cc1ccccc1)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=WDDOYUKTNGRVCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439339   

TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439339(4-(2-(4-(2-butyryl-5-chlorophenyl)-5-methoxy-2-oxo...)
Affinity DataIC50:  36nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439339(4-(2-(4-(2-butyryl-5-chlorophenyl)-5-methoxy-2-oxo...)
Affinity DataIC50:  36nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent