BDBM439368 4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)-3-(2-fluorophenyl)propanamido)benzoic acid::US10633375, Compound No. 68::US11084808, Compound 68

SMILES COc1cn(C(Cc2ccccc2F)C(=O)Nc2ccc(cc2)C(O)=O)c(=O)cc1-c1cc(Cl)ccc1C(C)=O

InChI Key InChIKey=OTQNYYTUVLSHHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439368   

TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439368(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50:  47nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439368(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50:  47nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent