BDBM439401 2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)-3-(1-cyclopropyl-1H-pyrazol-3-yl)-N-(quinoxalin-6-yl)propanamide::US10633375, Compound No. 96::US11084808, Compound 96

SMILES COc1cn(C(Cc2ccn(n2)C2CC2)C(=O)Nc2ccc3nccnc3c2)c(=O)cc1-c1cc(Cl)ccc1C(C)=O

InChI Key InChIKey=PCJMQCIDZJBECX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439401   

TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439401(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyri...)
Affinity DataIC50:  32nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439401(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyri...)
Affinity DataIC50:  32nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent