BDBM439579 N-ethyl-4-[4-(2-hydroxypropan-2-yl)-4′-(trifluoromethoxy) [1,1′-biphenyl]-2-yl]-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide::US10633379, Example 110

SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1-c1ccc(OC(F)(F)F)cc1)C(C)(C)O

InChI Key InChIKey=QLHCNZKHEKICHG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439579   

TargetBromodomain-containing protein 4 [352-457](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM439579(N-ethyl-4-[4-(2-hydroxypropan-2-yl)-4′-(trif...)
Affinity DataKi:  2nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [57-168](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM439579(N-ethyl-4-[4-(2-hydroxypropan-2-yl)-4′-(trif...)
Affinity DataKi:  224nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent