BDBM440792 US10639284, Compound 2.139::US10639284, Compound 3.120::US11426364, Compound 3.120

SMILES OC[C@H](NCc1cc(Cl)c(O[C@@H]2CCc3c2cccc3-c2ccccc2F)cc1OCc1cncc(c1)C#N)C(O)=O

InChI Key InChIKey=NMXWLVLSEKAWAF-URLMMPGGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 440792   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM440792(US10639284, Compound 2.139 | US10639284, Compound ...)
Affinity DataIC50: <100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM440792(US10639284, Compound 2.139 | US10639284, Compound ...)
Affinity DataIC50: <100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM440792(US10639284, Compound 2.139 | US10639284, Compound ...)
Affinity DataIC50: <100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM440792(US10639284, Compound 2.139 | US10639284, Compound ...)
Affinity DataIC50: <100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent