BDBM440986 US10640486, Example 20

SMILES Nc1nccc2[C@@H](CCc12)NC(=O)C1=CN(Cc2ccc(CN3CC4CCCN4C3=O)cc2)N=[N]1C(F)(F)F

InChI Key InChIKey=CUXNYAVQRCEDOF-BDPMCISCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 440986   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM440986(US10640486, Example 20)
Affinity DataIC50:  4nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent