BDBM441123 US10640495, Example I-458

SMILES CNC(=O)c1ccc(cn1)-c1nn(c(NC(=O)N[C@@H]2CN(CCOC)O[C@H]2c2ccc(F)c(F)c2)c1C)-c1ccccc1

InChI Key InChIKey=JRUNICXKNMTZEK-VPUSJEBWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441123   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM441123(US10640495, Example I-458)
Affinity DataIC50:  0.520nMAssay Description:Seven point five μL per well of human TrkA (PV3144, Lifetechnologies, final concentration: 1 nmol/L) suspended in the assay buffer (100 mmol/L 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent