BDBM441782 US10640533, Identification number CX13-500::US10640533, Table 1.29

SMILES COC[C@H](NC(=O)c1cc(CN2CCOCC2)on1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=BEJCFXNBQIMQOM-VAVWXBAFSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 441782   

TargetChymotrypsin-like protease CTRL-1(Homo sapiens (Human))
Centrax International

US Patent
LigandPNGBDBM441782(US10640533, Identification number CX13-500 | US106...)
Affinity DataIC50:  170nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Centrax International

US Patent
LigandPNGBDBM441782(US10640533, Identification number CX13-500 | US106...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane protease serine 11D(Homo sapiens (Human))
Centrax International

US Patent
LigandPNGBDBM441782(US10640533, Identification number CX13-500 | US106...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsin-like protease CTRL-1(Homo sapiens (Human))
Centrax International

US Patent
LigandPNGBDBM441782(US10640533, Identification number CX13-500 | US106...)
Affinity DataIC50:  121nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Centrax International

US Patent
LigandPNGBDBM441782(US10640533, Identification number CX13-500 | US106...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane protease serine 11D(Homo sapiens (Human))
Centrax International

US Patent
LigandPNGBDBM441782(US10640533, Identification number CX13-500 | US106...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent