BDBM442053 US10647708, Compound 42

SMILES Cc1nnc(o1)-c1ccc(cc1)C(=O)NCCC(O)CN1CCc2ccccc2C1

InChI Key InChIKey=HYTJZWQQQAVXOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442053   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442053(US10647708, Compound 42)
Affinity DataIC50:  2.83E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent