BDBM442282 US10647713, Compound I-243::US11396508, Compound I-243

SMILES Cc1nc2c(Nc3ccccc3P(C)(C)=O)cc(NC(=O)C3CC3)nc2[nH]1

InChI Key InChIKey=RCURRQUMVRNBGB-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442282   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM442282(US10647713, Compound I-243 | US11396508, Compound ...)
Affinity DataKd: >10nMAssay Description:The binding reaction was assembled by combining 16 μl of DNA-tagged kinase extract, 3.8 μl liganded affinity beads, and 0.18 μl test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM442282(US10647713, Compound I-243 | US11396508, Compound ...)
Affinity DataKd: >10nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent