BDBM442610 US10647713, Compound I-572::US11396508, Compound I-572

SMILES Cc1nc2c(Nc3ccc(cc3S(C)(=O)=O)C3CCC(F)(F)CO3)cc(NC(=O)C3CC3)nc2[nH]1

InChI Key

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442610   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM442610(US10647713, Compound I-572 | US11396508, Compound ...)
Affinity DataKd:  3.00E+5nMAssay Description:The binding reaction was assembled by combining 16 μl of DNA-tagged kinase extract, 3.8 μl liganded affinity beads, and 0.18 μl test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM442610(US10647713, Compound I-572 | US11396508, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent