BDBM442753 6-Chloro-N- {(1S)-[4- (trifluoromethyl)- phenyl]ethyl}- 1H-pyrazolo[3,4-d]- pyrimidin-4-amine::US10647727, Example 11

SMILES C[C@H](Nc1nc(Cl)nc2[nH]ncc12)c1ccc(cc1)C(F)(F)F

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442753   

TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442753(6-Chloro-N- {(1S)-[4- (trifluoromethyl)- phenyl]et...)
Affinity DataKi:  1.40E+3nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent