BDBM442758 6-Chloro-N-ethyl-1- methyl-N-[4- (trifluoromethyl)- benzyl]-1H-pyrazolo- [3,4-d]pyrimidin- 4-amine::US10647727, Example 16
SMILES CCN(Cc1ccc(cc1)C(F)(F)F)c1nc(Cl)nc2n(C)ncc12
InChI Key InChIKey=YUCXOPXWJQTIRR-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 442758
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 429nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Affinity DataKi: 866nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair