BDBM442781 N-{(1R)-1-[3-fluoro-4-(trifluoromethyl)phenyl]-2,2-dimethylpropyl}-2,9-dimethyl-9H-purin-6-amine::US10647727, Example 38
SMILES Cc1nc(N[C@H](c2ccc(c(F)c2)C(F)(F)F)C(C)(C)C)c2ncn(C)c2n1
InChI Key InChIKey=FYAOLVOVEZGUAJ-OAHLLOKOSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 442781
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 2.06E+3nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair