BDBM443283 2-Oxo-6-(trifluoromethyl)-1,4-dihydro-2H-spiro[pyrido[2,3-b]pyrazine-3,3′-pyrrolidine]-1′-carbonitrile::US10654853, Example 56::US11236092, Example 56

SMILES FC(F)(F)c1ccc2NC(=O)C3(CCN(C3)C#N)Nc2n1

InChI Key InChIKey=ZWXNQXPVMSIGMU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443283   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443283(2-Oxo-6-(trifluoromethyl)-1,4-dihydro-2H-spiro[pyr...)
Affinity DataIC50:  5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443283(2-Oxo-6-(trifluoromethyl)-1,4-dihydro-2H-spiro[pyr...)
Affinity DataIC50:  5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent