BDBM443334 6'-(1-Methyl-1H-indazol-5-yl)-2'-oxo- 1',4'-dihydro-2'H-spiro[pyrrolidine- 3,3'-quinoline]-1-carbonitrile::US10654853, Example 107::US11236092, Example 107

SMILES Cn1ncc2cc(ccc12)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key InChIKey=GUMBIBQYIWPWMC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443334   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443334(6'-(1-Methyl-1H-indazol-5-yl)-2'-oxo- 1',4'-dihydr...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443334(6'-(1-Methyl-1H-indazol-5-yl)-2'-oxo- 1',4'-dihydr...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443334(6'-(1-Methyl-1H-indazol-5-yl)-2'-oxo- 1',4'-dihydr...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent