BDBM444652 N-(3-(3-(4-phenoxyphenyl)-1H- pyrazolo[4,3-c]pyridin-1- yl)phenyl)acrylamide::US10662187, Compound 22::US10793566, Compound 22

SMILES C=CC(=O)Nc1cccc(c1)-n1nc(-c2ccc(Oc3ccccc3)cc2)c2cnccc12

InChI Key InChIKey=RHNAJPYATIALKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444652   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM444652(N-(3-(3-(4-phenoxyphenyl)-1H- pyrazolo[4,3-c]pyrid...)
Affinity DataIC50:  55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM444652(N-(3-(3-(4-phenoxyphenyl)-1H- pyrazolo[4,3-c]pyrid...)
Affinity DataIC50:  55nMAssay Description:Measurements were performed in a reaction volume of 15 μL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 μM peptide subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent