BDBM444654 (R)-1-(3-(3-(4-(2,3- dimethylphenoxy)phenyl)-1H- pyrazolo[4,3-c]pyridin-1-yl)piperidin-1- yl)prop-2-en-1-one::US10662187, Compound 24::US10793566, Compound 24

SMILES Cc1cccc(Oc2ccc(cc2)-c2nn([C@@H]3CCCN(C3)C(=O)C=C)c3ccncc23)c1C

InChI Key InChIKey=DDLFWGOXDXTLIM-JOCHJYFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444654   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM444654((R)-1-(3-(3-(4-(2,3- dimethylphenoxy)phenyl)-1H- p...)
Affinity DataIC50: <10nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM444654((R)-1-(3-(3-(4-(2,3- dimethylphenoxy)phenyl)-1H- p...)
Affinity DataIC50: <10nMAssay Description:Measurements were performed in a reaction volume of 15 μL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 μM peptide subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent