BDBM444849 6-((2-fluoro-5-methoxy-3'-(2,2,2-trifluoroethoxy)-4-::US10668067, Example 1-12

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ccon1)c1cc(F)c(cc1OC)-c1cccc(OCC(F)(F)F)c1

InChI Key InChIKey=PIGQQVMYSUGVET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444849   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM444849(6-((2-fluoro-5-methoxy-3'-(2,2,2-trifluoroethoxy)-...)
Affinity DataIC50:  85nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent