BDBM444897 6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluoromethyl)-4-::US10668067, Example 1-58
SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ccon1)c1cc(Cl)c(cc1OC)-c1ccc(F)c(c1)C(F)(F)F
InChI Key InChIKey=WOPREVPLYQFHHZ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 444897
Affinity DataIC50: 9nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human Nav1.7 by PatchXpress assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Time dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Time dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 30 minsMore data for this Ligand-Target Pair