BDBM444914 6-((2,4'-dichloro-3'-cyano-5-methoxy-4-::US10668067, Example 1-75

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ncccn1)c1cc(Cl)c(cc1OC)-c1ccc(Cl)c(c1)C#N

InChI Key InChIKey=IFAYMMRKDWAAHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444914   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM444914(6-((2,4'-dichloro-3'-cyano-5-methoxy-4- | US106680...)
Affinity DataIC50:  106nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent