BDBM444950 6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluoromethyl)-4-::US10668067, Example 3-9

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1cccc(F)n1)c1cc(Cl)c(cc1OC)-c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=MCZYKANPHLBZID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444950   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM444950(6-((2-chloro-4'-fluoro-5-methoxy-3'-(trifluorometh...)
Affinity DataIC50:  53nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent