BDBM444954 6-((2,4'-difluoro-5-methoxy-3'-(trifluoromethoxy)-4-::US10668067, Example 3-13
SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1cccnn1)c1cc(F)c(cc1OC)-c1ccc(F)c(OC(F)(F)F)c1
InChI Key InChIKey=HEMVNRUIGOXROO-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 444954
Affinity DataIC50: 7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Time dependent inhibition of CYP2D6 (unknown origin) incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human Nav1.7 by PatchXpress assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Time dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Time dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Time dependent inhibition of CYP2D6 (unknown origin) preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair