BDBM445011 US10668167, Compound 20

SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2cccc(N)c2)cc1

InChI Key InChIKey=RZCOQAQHAZHWEB-BFQQSILCSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 445011   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50:  19.4nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50:  18.6nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50:  814nMAssay Description:Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50: >3.00E+4nMAssay Description:Small molecules were tested for androgen receptor (AR) binding using a modification of the LanthaScreen® TR-FRET Androgen Receptor Coactivator Assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50:  8.60nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50:  17.1nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50:  3.00E+4nMAssay Description:Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50: >3.00E+4nMAssay Description:Small molecules were tested for androgen receptor (AR) binding using a modification of the LanthaScreen® TR-FRET Androgen Receptor Coactivator Assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent