BDBM445050 US10668167, Compound 62

SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Sc2ccc(Cl)c(N)c2)cc1

InChI Key InChIKey=QFXLFIGPPAXZQQ-JDYFQJKBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445050   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445050(US10668167, Compound 62)
Affinity DataIC50:  21nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445050(US10668167, Compound 62)
Affinity DataIC50: >3.00E+4nMAssay Description:Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445050(US10668167, Compound 62)
Affinity DataIC50:  24.8nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent