BDBM445172 (S)-1-cyano-N- methyl-N-(4-(6- (trifluoromethyl)- pyridin-2-yl)thiazol- 2-yl)-pyrrolidine- 2-carboxamide::US10669234, Example 82::US11319287, Example 82

SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1cccc(n1)C(F)(F)F

InChI Key InChIKey=IORAJTZSNAZPSA-LBPRGKRZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445172   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM445172((S)-1-cyano-N- methyl-N-(4-(6- (trifluoromethyl)- ...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM445172((S)-1-cyano-N- methyl-N-(4-(6- (trifluoromethyl)- ...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent