BDBM445306 (S)-3-(2-((1-(1-(3,5-difluoro-4-methylphenyl)-1H-imidazol-4-yl)cyclopropyl)amino)pyrimidine-4-1-methylimidazolidine-2-one::US10682352, Compound 32

SMILES CC(C)[C@H]1CN(C)C(=O)N1c1ccnc(NC2(CC2)c2cn(cn2)-c2cc(F)c(C)c(F)c2)n1

InChI Key InChIKey=ZCLPJLPMEIJTTE-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445306   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445306((S)-3-(2-((1-(1-(3,5-difluoro-4-methylphenyl)-1H-i...)
Affinity DataIC50: <100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent