BDBM445629 US10683294, Compound 1.034::US11479553, Compound 1.034
SMILES CCc1cccc(CC)c1-n1nc2c(CN(Cc3ccc(cc3C(F)(F)F)C(F)(F)F)C2(C)C)c1-c1cccc2[nH]cc(Cl)c12
InChI Key InChIKey=MVSYZAVOKJGDCT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 445629
Affinity DataIC50: 27.5nMAssay Description:To evaluate small organic molecules that prevent the C5a receptor from binding ligand, an assay was employed that detected radioactive ligand (i.e, C...More data for this Ligand-Target Pair
Affinity DataIC50: 27.5nMAssay Description:cAMP treated U937 cells expressing C5aR were centrifuged and resuspended in assay buffer (20 mM HEPES pH 7.1, 140 mM NaCl, 1 mM CaCl2, 5 mM MgCl2, an...More data for this Ligand-Target Pair