BDBM445640 US10683294, Compound 1.045::US11479553, Compound 1.045

SMILES CCc1cccc(CC)c1-n1nc2c(CN(Cc3ccc(cc3C(F)(F)F)C(F)(F)F)C2(C)C)c1-c1cccc2[nH]ccc12

InChI Key InChIKey=AYWAHWJIQJJFDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445640   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM445640(US10683294, Compound 1.045 | US11479553, Compound ...)
Affinity DataIC50:  27.5nMAssay Description:To evaluate small organic molecules that prevent the C5a receptor from binding ligand, an assay was employed that detected radioactive ligand (i.e, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM445640(US10683294, Compound 1.045 | US11479553, Compound ...)
Affinity DataIC50:  27.5nMAssay Description:cAMP treated U937 cells expressing C5aR were centrifuged and resuspended in assay buffer (20 mM HEPES pH 7.1, 140 mM NaCl, 1 mM CaCl2, 5 mM MgCl2, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent