BDBM445654 US10683294, Compound 1.059::US11479553, Compound 1.059
SMILES Cc1cccc(C)c1-n1nc2CN(Cc2c1-c1ccc2[nH]ccc2c1)C(=O)C1CCCC1
InChI Key InChIKey=NOBFUOGOIZVXSC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 445654
Affinity DataIC50: >500nMAssay Description:To evaluate small organic molecules that prevent the C5a receptor from binding ligand, an assay was employed that detected radioactive ligand (i.e, C...More data for this Ligand-Target Pair
Affinity DataIC50: >500nMAssay Description:cAMP treated U937 cells expressing C5aR were centrifuged and resuspended in assay buffer (20 mM HEPES pH 7.1, 140 mM NaCl, 1 mM CaCl2, 5 mM MgCl2, an...More data for this Ligand-Target Pair