BDBM445747 US10669240, Compound 43
SMILES O=C(Nc1cccc2cccnc12)c1n[nH]c2ccc(cc12)-c1cccnc1
InChI Key InChIKey=CCYLLLQTWUAUOU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 445747
Affinity DataIC50: 21nMAssay Description:Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...More data for this Ligand-Target Pair
Affinity DataIC50: 3.44E+3nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 8-point dose-response curves f...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed
US Patent
Samumed
US Patent
Affinity DataEC50: 2.20E+3nMAssay Description:SH-SY5Y cells are cultured in DMEM/F-12 medium supplemented with 15% FBS, Non-essential Amino Acid and Penicillin/Streptamycin. Two days before treat...More data for this Ligand-Target Pair