BDBM445758 US10669240, Compound 54

SMILES COc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cncc(CN3CCC(F)(F)C3)c2)cn1

InChI Key InChIKey=XHMCMYNTRDDSMY-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445758   

TargetProto-oncogene Wnt-1(Homo sapiens (human))
Samumed

US Patent
LigandPNGBDBM445758(US10669240, Compound 54)
Affinity DataIC50:  5nMAssay Description:Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPulmonary surfactant-associated protein A1(Human)
Samumed

US Patent
LigandPNGBDBM445758(US10669240, Compound 54)
Affinity DataIC50:  51nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 8-point dose-response curves f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM445758(US10669240, Compound 54)
Affinity DataEC50:  2nMAssay Description:SH-SY5Y cells are cultured in DMEM/F-12 medium supplemented with 15% FBS, Non-essential Amino Acid and Penicillin/Streptamycin. Two days before treat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent