BDBM446077 N-(2-{4-[(3,5-difluorophenyl)methoxy]piperidin-1-yl}-2-(4- methyl-1,3-thiazol-5-yl)ethyl)quinoline-5-carboxamide::US10669267, Compound 17
SMILES Cc1ncsc1C(CNC(=O)c1cccc2ncccc12)N1CCC(CC1)OCc1cc(F)cc(F)c1
InChI Key InChIKey=NQHIHSJMZCPHKH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 446077
Affinity DataIC50: 432nMAssay Description:Ca2+ influx was measured in HEK-293 cells stably transfected with the receptor using Screen Quest™ Fluo-8 No Wash Calcium Assay Kit (AAt Bioquest®). ...More data for this Ligand-Target Pair
Affinity DataIC50: 32.9nMAssay Description:In order to directly monitor the block of P2X7 channel, an electrophysiological assay was developed and implemented on the QPatch16X automated electr...More data for this Ligand-Target Pair