BDBM446090 2-chloro-N-{2-[4-(4-chlorophenoxy)piperidin-1-yl]-2-(4-methyl- 1,3-thiazol-5-yl)ethyl}-6-fluorobenzamide::US10669267, Compound 8

SMILES Cc1ncsc1C(CNC(=O)c1c(F)cccc1Cl)N1CCC(CC1)Oc1ccc(Cl)cc1

InChI Key InChIKey=UKDKUNRTLFYCRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446090   

TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Axxam

US Patent
LigandPNGBDBM446090(2-chloro-N-{2-[4-(4-chlorophenoxy)piperidin-1-yl]-...)
Affinity DataIC50:  1.31E+3nMAssay Description:Ca2+ influx was measured in HEK-293 cells stably transfected with the receptor using Screen Quest™ Fluo-8 No Wash Calcium Assay Kit (AAt Bioquest®). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent