BDBM447731 (R)-N-(1- cyanopyrrolidin- 3-yl)-3-(3,4- dimethylphenyl) isoxazole-5-::US10689345, Example 271

SMILES Cc1ccc(cc1C)-c1cc(on1)C(=O)N[C@H]1CCN(C1)C#N

InChI Key InChIKey=DGEZWOPHEMOPTB-AWEZNQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447731   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM447731((R)-N-(1- cyanopyrrolidin- 3-yl)-3-(3,4- dimethylp...)
Affinity DataIC50: <100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent