BDBM448042 US10689376, Compound 44::US11142524, Compound 44

SMILES COc1c(F)cc(NC(=O)CSc2nc3cnc(cc3[nH]2)C(F)(F)F)cc1F

InChI Key InChIKey=FUVVIKNHZVJKHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448042   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Stingray Therapeutics

US Patent
LigandPNGBDBM448042(US10689376, Compound 44 | US11142524, Compound 44)
Affinity DataIC50:  1.02E+4nMAssay Description:Materials:Assay Buffer: 1 mM CaCl2, 0.2 mM ZnCl2, 50 mM Tris, pH 9.0. Substrate: 8 mM Thymidine 5′-monophosphate p-nitrophenol ester sodium sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Stingray Therapeutics

US Patent
LigandPNGBDBM448042(US10689376, Compound 44 | US11142524, Compound 44)
Affinity DataIC50:  1.02E+4nMAssay Description:Materials: Assay Buffer: 1 mM CaCl2, 0.2 mM ZnCl2, 50 mM Tris, pH 9.0 Substrate: 8 mM Thymidine 5′-monophosphate p-nitrophenol es...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent