BDBM448064 US10689376, Compound 89::US11142524, Compound 89

SMILES COc1ccc(NC(=O)CSc2nc3cc(Cl)ncc3[nH]2)cc1OCC(F)(F)F

InChI Key InChIKey=DWXWEXDHZMDWNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448064   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Stingray Therapeutics

US Patent
LigandPNGBDBM448064(US10689376, Compound 89 | US11142524, Compound 89)
Affinity DataIC50:  1.13E+4nMAssay Description:Materials:Assay Buffer: 1 mM CaCl2, 0.2 mM ZnCl2, 50 mM Tris, pH 9.0. Substrate: 8 mM Thymidine 5′-monophosphate p-nitrophenol ester sodium sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Stingray Therapeutics

US Patent
LigandPNGBDBM448064(US10689376, Compound 89 | US11142524, Compound 89)
Affinity DataIC50:  1.13E+4nMAssay Description:Materials: Assay Buffer: 1 mM CaCl2, 0.2 mM ZnCl2, 50 mM Tris, pH 9.0 Substrate: 8 mM Thymidine 5′-monophosphate p-nitrophenol es...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent